Immunoglobulins (antibodies, gamma globulins) - compounds, which are produced by cells of the immune system.They protect man against various bacteria and viruses, as well as antigens.Immunoglobulin not only protects the human body, but also often used in medicine.In identifying the various pathologies apply quantitative and qualitative detection of antibodies of different classes.Immunoglobulin is a member of medicines, which are used for the prevention and treatment of infectious diseases.There
five classes of immunoglobulins: G, M, E, A and D, which differ in structure and functions performed.
Immunoglobulin G (IgG) refers to the major classes of immunoglobulins contained in serum.It has four subclasses (IgG1, IgG2, IgG3, IgG4), that perform their unique function independently.Immunoglobulin G begins to produce a few days after IgM and persists for a long time in the body, preventing an illness re sick and neutralizes harmful toxic substances.The small size allows it to penetrate without hindrance t
immunoglobulin M (IgM) is the first defender of the antigen as produced in contact with a foreign agent in the human body.Antibodies of class M is much larger, so the placenta in pregnant women does not penetrate to the child, and is found only in the blood of women.The number of IgM is about 10%.
Immunoglobulin E (IgE) in the blood is not observed practically.It participates in the event of an allergic reaction to protect against infections.He speaks of increasing the propensity to allergic diseases and atopy.
Immunoglobulin A (IgA) protects the mucous membranes of microorganisms and foreign substances, so it is also called secretory.It is located in the secretions of the lacrimal and salivary glands, the mucous membrane of respiratory and urogenital systems and in milk.Its concentration is about 20%.
Immunoglobulin D (IgD) refers to antibodies whose function is not yet fully clear, and the amount in the blood is extremely small (1%).They are mostly used in medical preparations, which can be purchased at any pharmacy.
blood test for immunoglobulin - a survey of the immune system in order to detect diseases in humans.It helps assess the state of the organism and the severity of the allergic disease, that is playing a major role in the appointment of proper treatment.
blood test for immune globulin is recommended for helminthiasis, hay fever, asthma, atopic dermatitis, eczema, drug and food allergies, with lingering, chronic or frequently recurring infections in suspected autoimmune diseases and cancer, immunodeficiency, as well as during the examination before surgeryor severe rehabilitation after her.
blood test for IgE
IgE antibodies responsible for allergic reactions.After exposure to the allergen it produces a release of serotonin, histamine and other active substances, due to the formation of specific complex on the cell surface, which leads to the emergence and development of inflammatory reactions and anaphylaxis manifestation.
main contents detected antibodies in the mucous membranes of the respiratory tract and gastrointestinal tract, and skin.
Norma immunoglobulin content in the blood serum is very low, ranging from 30 to 240 mg / l.The highest level of antibodies - in May, the lowest - in December.This is easily explained.Active spring there bloom most plants, which leads to saturation of the air with pollen (one of the strongest allergens).
immunoglobulin E occurs in humans after 10 weeks of fetal development.Its amount increases gradually from birth to adolescence.Older people gradually reduced its content.
sharp increase or decrease in IgE indicates the presence of certain diseases.
blood test for IgE rent in bronchial asthma, eczema, atopic dermatitis, hay fever, and helminthiasis.Study blood immunoglobulin is expedient to determine the presence of drug and food allergies, and children to identify possible genetic disorders if their relatives suffer allergic reactions.
high level of antibodies in the blood to immunoglobulin E in children suggests the possible presence of diseases such as hay fever, urticaria, atopic dermatitis, allergic rhinitis, food intolerance, drug allergies, infection with parasites, asthma, myeloma and other allergic diseases.
If a child a blood test for IgE dropped, the reasons can be hereditary hypogammaglobulinemia, certain types of tumors, or Louis-Bar syndrome (ataxia telangiectasia).
To analyze blood immunoglobulinproizvodyat special laboratory testing of blood serum.The results to be the most reliable, is necessary to properly prepare for a blood sample.Blood sampling is performed in the morning obligatory fasting.For the analysis of suitable venous blood, which is usually taken in the area of the elbow.It is advisable for a few days before the procedure to eliminate from the diet of alcohol, fatty and spicy foods, limit physical activity and possibly exclude smoking.When receiving any medical drugs should inform the specialist.
Decoding blood test for IgE
Normally, figures presented in deciphering the blood test for immunoglobulin E, have the following meanings:
- for children up to 3 months - 0 ... 2 Re / l;
- from 3 to 6 months - 3 ... 10 kE / l;
- children under one year - 8 ... 20 Re / l;
- kids from 1year to 5 years - 10 ... 50 Re / l;
- children from 5 years to 15 years - 16 ... 60 Re / l;
- adults - 20 ... 100 Re / l.
Deviations from these standards identified in the analysis of blood immunoglobulin E in children and adults, as a rule, indicate any disease or development of pathological processes in the body.